Jimpy

Jimpy
Mouse mutant with reduced life-span due to a recessive sex-linked defect in PLP gene. Has a severe CNS myelin deficiency associated with complex abnormalities affecting all glial populations. Jimpy-J4, the most severe of the jimpy mutants has virtually no PLP protein. See Pelizaeus-Merzbacher disease.

Dictionary of molecular biology. 2004.

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